Additional Resources

GlycoWorkbench

GlycoWorkbench is a software tool developed to assist the interpretation of MS data of glycans. The main task of GlycoWorkbench is to evaluate a set of structures proposed by the user by matching the corresponding list of fragment masses against the list of peaks derived from the spectrum. The tool provides an easy to use graphical interface and a broad set of features.

N-Zyme Scientifics

N-Zyme Scientifics is a development and supply company that specializes in enzymes used in Glycobiology-based applications and research in Pharmaceuticals, Diagnostics, Drug Discovery and Biologics. Their products are especially designed for advanced applications, particularly those using MALDI-Glycan Mass Spectrometry Imaging, UPLC/HPLC, and Hydrophilic Interaction Chromatography (HILIC).

Glycosmos

The GlyCosmos Portal is a web portal aiming to integrate glycosciences with life sciences. It consists of standards, repositories and data resources, and provides information about genes, proteins, lipids, pathways and diseases.

Additional Publications

Heijs B. et. al. MALDI-2 for the Enhanced Analysis of N-Linked Glycans by Mass Spectrometry Imaging. Anal. Chem. 2020,92, 13904-13911. PMID: 32975931.

Boyaval F. et. al. N glycomic signature of stage II colorectal cancer and its association with the tumor microenvironment. Mol Cell Proteomics 2020 Oct 20:mcp.RA120.002215. doi: 10.1074/mcp.RA120.002215. PMID: 33082215.

Biswas, B. et. al. Transgenic Rescue of Spermatogenesis in Males With Mgat1 Deleted in Germ Cells. Frontiers in Cell an Developmental Biology 8, 212 (2020). PMID: 32300591.

Briggs, M. T. et al. MALDI Mass Spectrometry Imaging of Early‐and Late‐Stage Serous Ovarian Cancer Tissue Reveals Stage‐Specific N‐Glycans. Proteomics 19, e1800482 (2019). PMID: 31364262.

Holst, S. et al. Linkage-specific in-situ sialic acid derivatization for N-Glycan Mass Spectrometry Imaging of FFPE tissues. Analytical Chemistry 88, 5904-5913 (2016). PMID: 27145236.

Everest-Dass, A. V. et al. N-Glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues. Molecular & Cellular Proteomics 15, 3003-3016. (2016). PMID: 27412689.

Voruganti S. et. al. A Detailed Protocol for Generation of Therapeutic Antibodies with Galactosylated Glycovariants at Laboratory Scale Using In-Vitro Glycoengineering Technology. J Pharm Sci. 2020 Oct 8:S0022 3549(20)30590-6. PMID: 33039440.

Heijs, B. et al. Multimodal mass spectrometry imaging of N-glycans and proteins from the same tissue section. Analytical Chemistry 88, 7745-7753. (2016). PMID: 27373711.

Biswas KB. et. al. GPNMB is expressed in Human Epidermal Keratinocytes but disappears in the Vitiligo Lesional skin. Sci Rep. 2020 Mar 18:10(1):4930. doi: 10.1038/s41598 020-61931-1. PMID: 32188902.

Esteban PF. et. al. Revisiting CB1 cannabinoid receptor detection and the exploration of its interacting partners. J Neurosci Methods. 2020 May 1;337:108680. doi: 10.1016/ j-jneumeth.2020.108680. Epub Mar 4. PMID: 32145227.

Watanabe K. et. al. Human soluble phospholipase A2 receptor is an inhibitor of the integrinmediated cell migratory response to collagen-I. Am J Physiol Cell Physiol. 2018 Sep 1;315(3):C398 C408. doi: 10.1152/ajpcell.00239.2017. PMID: 29791208.

Kutzner TJ. et. al. How presence of a signal peptide affects human galectins-1 and -4: Clues to explain common absence of a leader sequence among adhesion/growth-regulatory galectins. Biochim Biophys Acta Gen Subj. 2020 Jan;1864(1):129449. PMID: 31678146.

Oide S. et. al. Carbohydrate-binding property of a cell wall integrity and stress response component (WSC) domain of an alcohol oxidase from the rice blast pathogen Pyricularia oryzae. Enzyme Microbial Technology. 2019 Jun;125:13-20. PMID: 30885320.

Everest-Dass AV. et. al. Human Disease Glycomics: Technology Advances Enabling Protein Glycosylation Analysis - Part 1. Expert Rev Proteomics: 2018 Feb;15(2):165-182. PMID: 29285957.

Holst S. et. al. High Throughput and High-Sensitivity Mass Spectrometry-Based N-Glycomics of Mammalian Cells. Methods Mol Biol. 2017;1503:185-196. PMID: 27743367.

Sonneveld ME. et. al. Glycosylation pattern of anti-platelet IgG is stable during pregnancy and predicts clinical outcome in Alloimmune Thrombocytopenia. Br J Haematol. 2016 Jul;174(2):310-20. PMID: 27017954.

Holst S. et. al. N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type  Homebox 1 (CDX1)/Villin mRNA Expression. Mol Cell Proteomics. 2016 Jan;15(1):124-40. PMID: 26537799.